In the Babylon 5 universe, an organization founded near the end of 2261 after President Clark was ousted on Earth. The initial members of the Alliance are the humans, Centauri, Minbari, Narns, and the former League of Non-Aligned Worlds.

The Alliance's first President is John J. Sheridan. Delenn, Londo Mollari, and G'Kar (who wrote the Alliance's founding principles) are on the Advisory Board. Michael Garibaldi is head of Alliance covert operations.