, or 5-hydroxy-N,N-dimethyltryptamine)
and other related 5-hydroxy-indolethylamines
are common constituents in the venom
of several toad
families, most notably Hyla, Leptodactylus, Rana and Bufo.
The best known of these is probably Bufo Alvarius,
the Colorado River Toad
Bufotenine is not psychoactive in "reasonable doses",
but with higher doses dangerous physiological
side effects can manifest.
The safest way to consume it is to collect the venom
from the toad in question, e.g. on a glass plate.
The venom is viscous and milky-white in color when first squeezed from the glands. It begins to dry within minutes and acquires the color and texture of rubber cement. Scrape the venom from the glass plate, dry it thoroughly, and store it in an airtight container until you are ready to smoke it.
As with other tryptamines, the effects when smoked is
almost instantaneous, and can be felt already after the first
inhalation. All effects are usually completely gone within
one hour of intake.