A Spanish curse word -- somewhat difficult to translate. It is very rude. As an exclamation, I would translated it as "Fuck!" or "Goddamn!"; as a noun, "fucked", "stupid fuck", or "dick"; as an adjective, "fucked" or "damned".
It is really stronger than "damn". For a milder curse you can say "Barajo!" or maybe "Cará!" instead.