In
NetHack, blessed
items
have stronger or more useful
effects than the
uncursed versions. For some
items, the effects just last longer or work better; for example, a
potion of gain ability adds one point to a
random stat when
quaffed, but a blessed
potion of gain ability adds one to
all stats when
quaffed -- very useful. Some items should almost always be blessed before use, such as a
scroll of genocide.
To bless an item, dip it in holy water.