Read as milligrams per kilogram. Used to formulate doses of drugs or other substances that are relative to the subject's body weight. For example, if I weigh 60kg and want to take 50mg/kg of GHB, I will take (50*60)=3000mg.

Measuring in mg/kg (or g/kg, etc) reduces the risk that heavier or larger people will show reduced reactions just because the drug is more diluted in their system. This is common sense -- tall, musclebound people can drink small, slight ones under the table even when alcohol tolerance and other factors are held constant.