Abbreviation: 5-FU. An anti-cancer
agent similar in structure to the nitrogenous base thymine
, which inhibits the enzyme dihydrofolate reductase
(DHFR) and thus nucleotide synthesis
, so that it is particularly harmful to rapidly growing cells such as in tumor
From the BioTech Dictionary at http://biotech.icmb.utexas.edu/. For further information see the BioTech homenode.