A severe form of the genetic disorder thalassemia
in which all four alpha chain polypeptide
s making up the hemoglobin
molecule (the protein
which transports oxygen
in the body) are missing due to a defect
in the gene
which codes for them. As a result, affected individuals die
at or before birth.
From the BioTech Dictionary at http://biotech.icmb.utexas.edu/. For further information see the BioTech homenode.