The Grunstein and Hogness method is a hybridization lab technique
in which whole, lyse
d (ruptured) bacteria
l colonies which have previously been blotted onto a nitrocellulose
(or other) membrane
to a DNA probe
The information in this writeup was taken from the science dictionary at http://biotech.icmb.utexas.edu/; I oversaw the development of the dictionary. For copyright details, see the BioTech homenode.