Ketamine

The other day, a friend of mine found some Ketamine. Needless to say, my weekend has been a little messed up. I find K to be a little interesting, rather powerful, etc.

Preparation:

Assuming you have a bottle with the syringe type opening, get a syringe, and suck a nice measured amount into the tube. Measure based on the mg of K versus ml of liquid. Check erowid.org for good dosage measurements. Then squirt it out into a spoon and boil it off over a candle. A powdery type crust will be left on the spoon. Scrape that off and dice it with a razor blade.

Doing it

Just snort it.

Feeling it

Personally, I would consider K to be more of a novelty drug than a mind expanding one. I took it the last couple of nights, and it really made me tired afterward. It does do some strange things, that I would consider textbook disassociation, but then again, I have never tried PCP.

Be warned, it is a Schedule III controlled substance.

I agree with nutate that ketamine's no mind-expander. But it's great for chilling, preferably with some friends.

Be warned: you will not be motivated to do anything at all, for pretty much any reason, while under the influence of this drug. I distinctly remember that I couldn't be bothered to reach for the remote when a shitty tv show came on.

The intense hallucinations mentioned above are brought on by injection. You don't have to do this intravenously, you can just inject it intramuscularly. The trip thus produced is far more intense than anything brought about by mushrooms or LSD.

I did this once, and I had no idea what other world I was in. When I finally came to, I found myself staring at a screen saver. Someone else I was with completely lost his shit, and refused to give us another kid's K. He was extremely paranoid and very difficult to talk to. When he spoke, each word was understandable, but the sentence as a whole was not.

Most people snort K, however. This I have never found to produce hallucinations. It just makes you feel weird, as adequately described above. I'll just add that when I dance on K, I get this sort of out of body experience. It's really cool, but not cool enough to be addictive.

Ketamine is a dissociative anesthetic and non-competitive NMDA antagonist. In addition to its use as an anesthetic, ketamine is also used as a research tool in modelling disorders such as schizophrenia. In at least one study, it was shown to activate the area of the prefrontal cortex linked to schizophrenia. It is also used as a model of the near-death experience.

Ketamine works by binding to and blocking glutamate receptors. It also inhibits reuptake of serotonin and noradrenalin, as well as activating serotonin metabolism and increasing subcortical release of dopamine.

Chemical structure:

     H   H
      \ /
    H--C
  H  H  \ H  O H   H
   \  \  \|  \\ \ /
    C--C  N   C--C   H
   //  \\  \ /    \ /
H-C      C--C      C
   \    /    \    / \
    C==C      C--C   H
   /    \    /|  |\
  H     Cl  H H  H H

Sources:
http://ams.cu.edu.tr/January1998Vol7No1/ketamine.htm
http://www.biopsychiatry.com/ketamine.htm