To annoy someone, especially by provoking, irking, and pestering them. Telemarketers are especially good at this, as are spammers, flamers, and some siblings. Bother can also be a noun, describing someone or something that is bothering you.

It's also fun to say, "Oh, bother!" when things bug you. If you say it in a high-pitched, gravelly voice like Sterling Holloway, everyone will think of Winnie the Pooh. And everyone loves Pooh! (except that psychopath Rabbit, who's plotting the little honeypot's demise)