For every 3500 calories you consume, you gain one pound. For every 3500 calories of effort you exert, you lose one pound.

This is why low-fat diets don't work, why high-protein diets don't work, and why nearly every single diet fails. Regardless of what form of food you eat, every 3500 calories you eat, whether it's a salad or a bucket of lard, makes you gain a pound. And every 3500 calories of work, whether it's climbing stairs or sitting on your ass watching tv for a week, makes you lose one pound.

So how do you lose weight? Exert more energy than you consume. It's that simple. Yes, even if you have a glandular disorder, the equation is the same:

(Calories in) - (Calories out)
-------------------------------       = Pounds gained.