Little Blue is the name of a "lake" near Chester, West Virginia. However, unlike typical bodies of water in this region, the water is crystal clear and is tinted a bright blue, much like the water at a tropical beach. All vegetation in the lake is dead, no animals are able to survive in it, and it has a horrible odor.
The strange blue color is most likely due to the fact that Little Blue is used as a fly ash settling pond. Fly ash is a coal combustion byproduct. The property was bought by a coal power plant in Shippingport, Pennsylvania and terraformed into the lake many years ago. Overall it is a bizarre sight in the middle of a bizarre state.