Perhaps notable here is the motto of the software company Connectix, coined while creating the x86 emulator Virtual PC:
"Endian little hate we."
The original Virtual PC was written for the Macintosh, a big-endian architecture. Needless to say, emulating a little-endian architecture on a big-endian one has its share of problems. Thus, the phrase was born. Also perhaps somewhat indicative of the idea that little-endian is usually much harder to understand, at least initially, for people who write numbers starting with the most significant digit.