Tristram is a town in the land of Khanduras, in the world of Sanctuary, the setting of Diablo and Diablo II. By the time you get there, in Diablo I, most of the inhabitants have moved out (thanks to a Prime Evil inhabiting their church). Only a few remain (a healer, a witch, a thief, a drunkard, a blacksmith, etc.), and you, consequently, are their last hope.

All of Diablo I is set in (or under) Tristram, but in Diablo II, you only spend a short time there. Here are a listing of NPCs/townsfolk that you will meet:
Tristram is unique in that the inhabitants never, ever move. Neither does the water, for that matter. It's also rather odd that there's an entrance into hell behind Pepin's house.

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