An extremely important tool employed by the Ghostbusters in their search for and elimination of supernatural entities.

Though it is uncertain how old the Spirit Guide is, it seems to contain every known and surviving piece of information on anything even remotely occult related. Ranging from how to dispel zombies, cure werewolves and stop a headless horseman all the way up to Gozer, Vigo and the Necronomicon, the guide is indispensible to both the original Ghostbusters and the newer incarnation Ghostbusters Extreme.

A new version of the Guide is being compiled by Egon Spengler for use by the Ghostbusters Extreme under the title of Spengler's Spirit Guide

The guide itself is referenced in both Ghostbusters and Ghostbusters II as well as almost every episode of The Real Ghostbusters.

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