Katharine Drexel is the second person born in the United States to be recognized as a saint by the Roman Catholic Church. (Do you know who the first one is?)
Born to privilege, she took a vow of poverty and used her wealth to found the Sisters of the Blessed Sacrament. She dedicated her life to helping Native Americans and African Americans, founding a number of schools around the United States, including Xavier University of Louisiana.
After her death, two healing miracles were attributed to her, and on October 1, 2000, she was canonized by the Pope.