The city of Duckberg is the setting for many adventures involving various Disney characters. For example, Donald Duck has a ton of his adventures in Duckberg. The city's name is even used in the ancient Sierra game Donald Duck's Playground.

More noticably, however, Duckberg is home to characters Scrooge McDuck, Launchpad McQuack, and the infamous Beagle Boys in the TV show DuckTales. Although most of the adventuring took place in locations outside of Duckberg, it still served as Scrooge's home and "safe haven". Safe, were it not for people like Flintheart Glomgold and Magica deSpell, who would constantly try to steal from Scrooge's money bin.