Highway 17 in California runs NE/SW between Santa Cruz and San Jose.
Since it's the only straight shot from the SC Bay to Silicon Valley, it's popular with commuters despite an apparent tendency for over-confident Volvo drivers to cause nasty, road-blocking accidents. It's curvy for the area, although it's no Highway 1.
There's not much on the way besides lovely redwoods and hills. It looms large in the local imagination, though, and there are several web pages devoted to it (listed at http://www.cruzio.com/~scva/rsward_hwy17.html ). The trail that it roughly follows across the Santa Cruz mountains dates to 1791.