An interaction between chemicals in which one partially or completely inhibits the effect of the other (e.g., a drug that blocks a hormone's receptor site would be a hormone antagonist).

From the BioTech Dictionary at http://biotech.icmb.utexas.edu/. For further information see the BioTech homenode.

An*tag"o*nism (#), n. [Gr. , fr. to struggle against; against + to contend or struggle, contest: cf. F. antagonisme. See Agony.]

Opposition of action; counteraction or contrariety of things or principles.

⇒ We speak of antagonism between two things, to or against a thing, and sometimes with a thing.

 

© Webster 1913.

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