If you're one of those who never got into South Park I certainly don't envy you. Once you've gotten familiar with the crude humor the show is primarily known for you'll find layers of self-consciousness, critical eye on the world's affairs, and, most prominently to me, hilariously over-the-top character grotesques. If you want to see an idea taken to the extreme and at the same time strapped bare and exposed to all the allusions we connect with it, South Park is the way to go.
An often overlooked aspect of the series is, with the main characters being 3rd/4th graders, that many scenes and episodes deal with the kids' eye view on the world. It's not presented in a sentimental form though - it's usually delivered in a tongue-in-cheek manner that shows how kids actually act very rationally in their own way, and that our idealistic view on their behavior has the same source as their behavior - different interests and lack of information. Children know when they don't know, their parents are often not able to face it. Prominently, it also happens that the so-called grown-ups are way more ridiculously infantile than the kids they are supposed to take care of. On many occasions - while their parents are going ape - the children, especially Kyle Broflowski and Stan Marsh (characters loosely based on the creators Matt Stone and Trey Parker) seem like the only individuals to remain reasonable.
South Park regularly projects the message that the details behind most beliefs, mind sets, religions, mentalities, fears, myths, philosophies, pop culture phenomena, political ideas, nations, industries, scenes, even scientific methods, are, especially if compared conceptually to others, ridiculous and laughable when taken for granted and word by word. This cultural awareness that takes nothing as dead serious and at the same time tries to find an essential truth - and knowing when it is failing at that - in the most absurd scenarios - is what makes this show extremely liberating and astounding.