Quetiapine (brand name Seroquel) is an atypical antipsychotic drug developed by Zeneca with the chemical formula C42H50N6O4S2. It is classed as a dibenzothiazepine and used in the treatment of schizophrenia. The daily dosage range is between 300 and 450 mg, split into 2 doses.
Quetiapine has a greater affinity for 5-HT2 receptors than D2 receptors, which is thought to be the reason for the drug causing less extrapyramidal symptoms. Somnolence is the most common side effect.
Chemical strucutre:
H H H H H
\| |/ \
H H C--C H C--O--H
\ \ / \ \ / \
H C--N+ O--C H
\ / \ \
C C--H H
/ \ / \
H N--C H
/ /|
H N==C H H H
\ / \ /
C--C C---C
// \\ // \\
H--C C C C
\ / \ / \ / \
C==C S C==C H
/ \ / \
H H H H
Sources:
http://www.priory.com/focus4.htm
http://www.biopsychiatry.com/quetschizo.htm