The girl character in the comic strip
Calvin and Hobbes. She is described by the creator,
Bill Watterson as
"earnest, serious and smart - the kind of girl I was attracted to in school and eventually married". *Derkins* is Watterson's wife's family's beagle's
nickname.
Calvin is always trying to annoy Susie... like by forming the club:
G.R.O.S.S. = Get Rid Of Slimy girlS.