Brand/Generic Drug Names

Amphojel/aluminum hydroxide, Tums/calcium carbonate, Riopan/magaldrate, Maalox/magnesium oxide, Soda Mint/sodium bicarbonate, Phosphaljel/aluminum phosphate, Rolaids/dihydroxyaluminum sodium carbonate, Phillips’ Milk of Magnesia/magnesium hydroxide (ok, so I didn't put your favorite in - sorry - there are ca. twelve gazillion OTC brands!)
Common uses
decreased hyperacidity in peptic ulcer disease, reflux esophagitis, gastritis, hiatal hernia
basic compounds which neutralize gastric acidity and decrease rate of gastric emptying (aluminum, magnesium, calcium compounds)
Class contraindications
magnesium or aluminum hypersensitivity
Class precautions
magnesium: renal insufficiency, pregnancy, lactation
sodium content may be high; hypertension, congestive heart failure, low-sodium diet
Increased effect: quinidine, amphetamines, pseudoephedrine, levodopa, valproic acid, dicumarol
Decreased effect: cimetidine, corticosteroids, ranitidine, iron salts, phenothiazines, phenytoin, digoxin, tetracyclines, ketoconazole, salicylates, isoniazid
Adverse Reactions
aluminum: constipation, fecal impaction, bowel obstruction
magnesium: diarrhea
calcium: constipation, diarrhea
Carbonates: alkalosis, belching, abdominal distention, flatulence, alkaluria, electrolyte disturbances, rebound hyperacidity, milk-alkali syndrome
Additional Information
Assess aggravating/alleviating factors
Identify location, duration, characteristics of epigastric pain
Assess gastrointestinal symptoms; if fever and severe abdominal pain are present, do not give
Assess renal symptoms, urinary pH, electrolytes
Administer with 8 oz glass of water
Evaluate therapeutic response: decreased acidity and pain
Date of most recent Update
August 06, 2002
Further information is available in the writeup for the specific name(s) of this medication class