Xylitol (also known as xylite, birch sugar, koivusokeri) (CH2OH(CHOH)3CH2OH) is a naturally occuring sugar alcohol found in berries, fruit, vegetables and mushrooms. For example raspberry, strawberry, yellow plum and endive (as well as human tissue) contain xylitol in small amounts. Most xylitol is extracted from birch wood.

Xylitol is slowly and only partially absorbed by the body -- this makes it an excellent sweetener candidate for diabetics. There are concerns -- see Safety Issues below. Xylitol has been shown to be anticariogenic (prevent tooth decay), reduce gingivitis (gum disease) in adults and help prevent ear infections.

Chemical Composition

  CH2OH
  |
 HCOH
  |
HOCH
  |
 HCOH
  |
  CH2OH

History

Discovered almost simultaneously in the late 19th Century by German and French chemists, xylitol has been used for decades as a sweetener for diabetics in Russia. In China, xylitol is used fairly extensively for medical purposes.

Xylitol-Jenkki, the first xylitol chewing gum in the world, was launched by the Finnish company Leaf in 1975. Today, xylitol can be found in chewing gums (Trident, XyliFresh), toothpaste (Arm & Hammer, Pepsodent) as well as mouthwashes and candies.

Benefits

Unlike other sweeteners (sobritol (C6H8(OH)6), fructose (C6H12O5) or glucose (C6H12O6), for example), xylitol has five instead of six carbon atoms -- most bacterias in the mouth (including Streptococcus mutans) are unable to metabolise it. Xylitol also stimulates saliva secretion and raises the pH (lowers the acidity) of the mouth, making it less hospitable to S. mutans.

Xylitol also inhibits the growth of Streptococcus pneumoniae, a bacteria responsible for ear infections.

Dosage

Studies on the effectiveness of xylitol involved doses ranging from 4 to 10 grams daily -- this corresponds to 3 to 8 pieces of xylitol-laced chewing gum.

Safety Issues

Xylitol is believed to be safe, although daily doses higher than 30 grams can cause stomach discomfort or diarrhea. Note that other sugar alcohols carry the same caveat -- by order of the FDA, products containing a certain amount (that amount which makes it conceivable that 50 grams of sorbitol or 20 grams of mannitol may be ingested in 24 hours) must bear the warning, 'Excess consumption may have laxative effect'.

Xylitol is classified 'Miscellaneous/Food additive for which a petition has been filed and a regulation issued,' in the FDA's 2001 Investigations Operations Manual, with the comment:

[Provided that an] Amt used is not > that required to produce its intended effect -- May be safely used in foods for special dietary uses.
Source:
Xylitol FAQ:
http://www.xylitol.net/english/faq.cfm
Xylitol Study (Korean):
http://www.xylitolstudy.co.kr
Microhydron.Com:
http://www.microhydron.com/xylitol.htm
AccessScience@McGraw-Hill:
http://www.accessscience.com
Healing People -- Herbs & Supplements: Xylitol
http://www.healingpeople.com/hp_html/primapub/pg000288.htm
United States Food and Drug Administration Web Site:
http://www.fda.gov
Health & Healing
http://www.microhydron.com/xylitol.htm
Hildebrandt GH, Sparks BS. Maintaining mutans streptococci suppression with xylitol chewing gum. J Am Dent Assoc. 2000;131:909-916.
Uhari M, Kontiokari T, Niemela. A novel use of xylitol sugar in preventing acute otitis media. Pediatrics. 1998;102:879-884.