A monophonic analog modular synthesizer. The most complex and expensive unit in the MS line. Its production started in 1979.

Unlike the MS-10 and MS-20, there is no hard wired patching, which means all routing is done with patch cords. Designed to be an expander, the MS-50 has no keyboard and can communicate with other devices using both Hz/volt and volt/octave interfaces.

The MS-50 offers 1 VCO (with pink & white noise), 2 VCFs (low-/hi-pass), 1 LFO and two invertable ADSR envelope generators per voice. Other features include a ring modulator, a signal inverter, a voltmeter and sample/hold. The MS-50 is designed to be used with the SQ-10 sequencer.