"Everyone knows what is in room 101."
In George Orwell's fantastic and gripping satirical book 1984, room 101 is the ultimate torture chamber in the Ministry of Freedom building in Airstrip One (London). Here, deviators are tortured with the thing they most hate and fear, for example some plague rats on their face.
Room 101 is also a British comedy on BBC TV, where Nick Hancock (but now Paul Merton) interviews guests, giving the guest a chance to put the six things they most hate (like football, parties, and Portsmouth) into a notional Room 101.