It is also interesting to note that Sishio Makoto (clearly a villain, NOT an anti-hero. Huge difference. Also, Family name comes first in Japanese, every verbal referance to Shishio in the anime was spoken "Shishio Makoto".) was chosen to replace Kenshin as the Ishin party's lead assasin, after Kenshin vows never to kill again. We see him briefly in the OAV, at the very end, cutting down Lizuka on Katsura's orders for betraying Kenshin and Tomoe. Later on, the Ishin party abandoned him in a burning building, making the animosity against Kenshin personal as well as political.