A memeber of the Marvel Universe, specifically the X-Men aspect of it. The Blob was a staple in the cartoon, comic, and video game aspect of the X-Men. The Blob also made an appearance in the Spider Man aspect of the universe as well.

Fred Dukes began to use his mutant powers in a freak show, where his oversized body and mass attracted many visitors. His life would stay like this if not for Magneto. When the master of magnetism was forming the first Brotherhood of Evil Mutants, he went for Dukes. Then he learned how to use his powers in evil ways, controlling his density to make himself immovable and to trap others inside his fat. He, along with the other members of the Brotherhood, became one of the X-Men worse enemies, fighting many times against them.

After Magneto left the leadership of the Brotherhood, Mystique became their leader. Their first mission was to kill Senator Kelly, but the New X-Men stopped him and the other. The Blob was arrested, but set free some time after by Mystique and Rogue. Some months later, when the government offered the Brotherhood to become the Freedom Force, Blob turned into a worker of the government, but not for a long time. During a mission to save a scientist, almost all of the Freedom Force members died fighting against the group that had kidnapped the scientist. Blob and Pyro escaped. They both returned to the Brotherhood when Toad formed the third incarnation of the team. This Brotherhood did not make many problems, and the Blob vanished for some time.

Fred recently returned, fighting with X-Force with his powers enhanced by Onslaught. X-Force defeated him, but the Mimic saved Fred. This two fought Warpth and Risque and it seems that he, the Mimic and Risque used to work for the same man and that Fred and the Mimic are still working for him. In addition, the Blob showed up and fought Maverick, after a bar discussion.

In his last appearance, Blob was a member of a Brotherhood that liberated Xavier from the Hulkbuster Base. Cerebro captured this group, and their whereabouts are unknown.