A now-common drug used to treat Lupus is hydroxychloroquine, or branded as Planquinil. It is an early anti-malarial drug that was discovered to have healing effects for rheumatic and arthritic symptoms. It most often needs to be taken twice a day, and is mainly prescribed to systemic Lupus patients.

Also, several steroids are used to treat Lupus patients, including Prednisone, until the hydroxychloroquine takes effect on the human body, which can take anywhere from fifteen to twenty weeks.