Termination with extreme prejudice refers to is supposed to refer only to the
assasination of one's own
employee. Generally used in
espionage circles, although it's certainly
possible for any particularly
unethical employer to apply it.
It's meant to be a bit of a pun on the phrase "termination with prejudice," with the "termination" in this case referring both to the end of the employee's employment with that particular employer, as well as to the end of their life. In espionage and military circles, though, it is never used to describe killing a foreign agent.