The new series,
Enterprise, will take place in the 2150s. To give you ignorant people some idea of when that is, the
Federation and
Starfleet were established in
2161 and the
USS Enterprise was launched in
2245 and
Kirk got command in
2264.
Anyway...this series is in the 2150s. First contact with the Klingons was in 2218, about 60 years later.
Guess what Enterprise's first episode, "Broken Bow," will be about.
Yep, you guessed it: first contact with the Klingon Empire.