In my experience Depakote works best for
migraine headaches when
rapidly
infused. Anything longer than five minutes when used
intravenously doesn't work.
In fact I once had a nurse stand on a chair after tapping my vein and simply squeezed the bag as hard as she could until the contents were empty, less than a minute later. One of the side effects of this treatment is it tends to make you nauseous, but for those who have had migraines, you know side effects are of little consequence as long as the damn headache is gone.