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Antianginals
Brand/Generic Drug Names
amyl nitrate, isosorbide, Nitro-Tabs/nitroglycerin, atenolol, dipyramidole, metoprolol, propranolol, amlodipine, Cardizem/diltiazem, Procardia/nifedipine, Calan/verapamil
chronic stable angina pectoris, unstable angina, vasospastic angina; some are used in dysrhythmias and hypertension
Nitrates: dilate coronary and systemic arteries, causing decreased pre- and afterload Calcium channel blockers: dilate coronary arteries, decrease SA/AV node conduction beta-adrenergic blockers: decrease heart rate to decrease myocardial oxygen use dipyramidole: selectively dilates coronary arteries to increase coronary blood flow
known hypersensitivity, increased intracranial pressure, cerebral hemorrhage
postural hypotension, pregnancy, lactation, children, renal disease, hepatic injury
varies by drug
postural hypotension, headache, flushing, dizziness, nausea, edema, drowsiness, rash, dysrhythmias, fatigue
Assess orthostatic blood pressure, pulses Assess pain: duration, onset, character, activity at onset Evaluate therapeutic response: decrease/prevention of pain
August 06, 2002
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