It is widely believed (especially in Western Massachusetts) that each of the characters in the cartoon Scooby-Doo represents one of each of the Five Colleges Consortium when the show was started. The theory goes like:

There are all sorts of crazy theories to back this up, many of which revolve around "scooby snacks" being either drugs themselves, or taken because of the munchies. These theories are interesting and widely spread, but mostly maintained to be false.

The show was originally mentioned to be based off of The Many Loves of Dobie Gillis, where Fred is based off of Dobie, Shaggy on Maynard, Velma on Zelda, and Daphne on Thalia. Hannah-Barbara based their cartoons off of successful TV shows (the Flintstones was based off of The Honeymooners)

According to Glowing Fish there is a similar myth concerning the Claremont Colleges.

The specifics of this myth, and its debunking can be found at:

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