's Wheel of Time
Sa'Angreal, the older brother of Angreal, were produced by Aes Sedai and all evidence points to the fact
that the creation of these were a great undertaking made by Male and Female Aes Sedai working together in harmony.
Unlike Ter'Angreal and Angreal where there are still hundreds of each in existance, There are very few Sa'Angreal in the world of the Breaking.
Two of these take the form of giant statues half buried the ground, one of a male, one of a female, both holding along spheres
aloft. These are the most powerful Sa'Angreal ever created, and were never used because they contain the power to rip the world
asunder. These can be activated from a remote location by using a small Ter'Angreal that acts basically like a remote control,
not surprisingly, the female statue is for use by a female, and thus draws and holds saidar for her, while the male statue draws
and holds saidin.
A third Sa'Angreal is known as Callandor or The Sword That Is Not a Sword, The Sword That Cannont Be Touched. It features prominently in the Prophecies of the Dragon.
As Inoshira_K and Palpz both just pointed out, The White Tower has at least a 'few' Sa`Angreal and Siuan uses one to cure Mat in the Dragon Reborn.