Tibetan Unicode: ༀ'མཎི'པདེྨ'ཧཱུྃ ༔
Literally, "Om! The jewel is in the lotus."
Om mani padme hum is a Sanskrit mantra chanted by many Buddhists in order to appeal to Avalokitesvara, the jewel in the lotus. It is a reference to the Lotus Sutra, meant to be called upon for almost any type of support, such as wisdom, health, material things, and so on. It is also referred to by some as "The Great Bright Mantra" or the "Mantra of Universal Protection." Om mani padme hum is the national mantra of Tibet.
"The benefits of reciting OM MANI PADME HUM are like the infinite sky. Depending on how perfectly qualified one's mind is and on one's motivation, even reciting OM MANI PADME HUM one time can purify negative karma. For example, a fully ordained monk who has received all four defeats can completely purify that very heavy negative karma by reciting OM MANI PADME HUM one time. So it is very powerful." - Lama Zopa Rinpoche