Do our choices matter? Paradoxically, yes it still does since our choices also affects what will follow.
This is not to be mistaken for fatalism or an excuse to not make choices, which you will soon realize is in itself a choice.
Why point this out then? Well, Sapolsky seems to be suggesting that giving this idea some thought might lead us to a more humane way of dealing with each other. If your actions do not come from you alone then maybe we can be more forgiving of others when we are "wronged".
The implications are huge and far reaching. The justice system will have to be reconfigured. No one is suggesting we let harmful people free but that perhaps removing
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