An emotional condition sparked in people usually in their 30's and 40's, pronounced by an intense boredom with their lives, jobs, or their partners. A great example of this phenomenon can be found in the 1991 movie City Slickers where three men go on a cattle drive to search for new meaning in their lives. It does appear that either sex can be affected although the male version is more acute.Unfortunately the author of ths w/u is suffering from the aforementioned affliction which may at least explain in part his shortage of activity on e2. Of course there is a semi-cure for this known as Prozac.