The Code of Federal Regulations (CFR) in its paper form is a giant stack of books containing all of the permanent rules and regulations published in the Federal Register by the Executive departments and agencies of the United States Federal Government. It is made up of 50 titles, most having several volumes, each representing a general subject area. Each title is revised at least once a year and issued on a quarterly basis (there's just too darn much to publish it all at once). The approximate date for publication of revisions is as follows:
Title 1 through Title 16--January 1
Title 17 through Title 27--April 1
Title 28 through Title 41--July 1
Title 42 through Title 50--October 1

References to the CFR take the form of xx CFR yy.zz, where xx is the title number, yy is the sub-part, and zz is the section. 21 CFR 11.100 would be a reference to:
Title 21--Food and Drugs
Chapter I--Food and Drug Administration, Department of Health and Human Services
Part 11--Electronic Records, Electronic Signatures
Section 100--General Requirements
For some reason unknown to me, the chapter number does not appear in a CFR reference.

The 50 CFR titles are as follows:

  1. General Provisions
  2. (Reserved)
  3. The President
  4. Accounts
  5. Administrative Personnel
  6. Economic Stabalization (Reserved)
  7. Agriculture
  8. Aliens and Nationality
  9. Animals and Animal Products
  10. Energy
  11. Federal Elections
  12. Banks and Banking
  13. Business Credit and Assistance
  14. Aeronautics and Space
  15. Commerce and Foreign Trade
  16. Commercial Practices
  17. Commodity and Securites Exchanges
  18. Conservation of Power and Water Resources
  19. Customs Duties
  20. Employees' Benefits
  21. Food and Drugs
  22. Foreign Relations
  23. Highways
  24. Housing and Urban Development
  25. Indians
  26. Internal Revenue
  27. Alcohol, Tobacco Products and Firearms
  28. Judicial Administration
  29. Labor
  30. Mineral Resources
  31. Money and Finance: Treasury
  32. National Defense
  33. Navigation and Navigable Waters
  34. Education
  35. Panama Canal
  36. Parks, Forests and Public Property
  37. Patents, Trademarks, and Copyrights
  38. Pensions, Bonuses, and Veteran's Relief
  39. Postal Service
  40. Protection of Environment
  41. Public Contracts and Property Management
  42. Public Health
  43. Public Lands: Interior
  44. Emergency Management and Assistance
  45. Public Welfare
  46. Shipping
  47. Telecommunication
  48. Federal Acquisition Regulations System
  49. Transportation
  50. Wildlife and Fisheries

A searchable database of the CFR is maintained by the National Archives and Records Administration and is available online at
http://www.access.gpo.gov/nara/cfr/cfr-retrieve.html