Here are a few tidbits about SiP:
The art of Strangers in Paradise, while cartoony, is more realisitic in its portrayal of body-types than most comics out there. Its women don't have triple E cups and its men don't have forty inch biceps.
One of the most overlooked aspects of Terry Moore's art is its often cinematic quality. There are a number of sequences that read as smoothly as watching a moving picture.
As for the stories, they don't fit any one genre, or, at least they jump among romance, soap opera, government conspiracy, and slice-of-life.