Isomerases are a broad class of enzymes which catalyze structural change in a single molecule in biological systems. These structural changes can be extremely various, from very simple modifications such as the reorientation from levo to dextro alignment in the following amino acid:


     COO-       alanine          COO-  
      |         racemase          |
H3N+--C--H      ------>         H--C--N+H3
      |                           |
     CH3                         CH3
  L-alanine                    D-alanine


Up to the fantastically complex topology topological modifications in DNA Topoisomerases, which uncoil and recoil long strands of DNA to allow reading and copying.

Log in or register to write something here or to contact authors.