To expand on the esteemed Webster:

Hyoscine is an alkaloid derived from the henbane plant, similar in action to atropine. It is an antispasmodic, a hypnotic, and a mild diuretic in small doses (up to 1/70 grain). Larger amounts can cause dizziness, hallucinations, delerium, convulsions, and death.

Although hyoscine is less well known than other alkaloids, such as belladonna and atropine, it was notorious for a time as the poison used by Hawley Harvey Crippen to murder his wife Cora in 1910.

Also spelled hyocine.


Source: Taylor's Principles and Practice of Medical Jurisprudence

Hy*os"cine (?), n. [See Hyoscyamus.] Chem.

An alkaloid found with hyoscyamine (with which it is also isomeric) in henbane, and extracted as a white, amorphous, semisolid substance.

 

© Webster 1913.

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