A disorder in which the skin is very rough and dry. The most common form is known also as ichthyosis simplex, in which large corrugated papery scales form on the skin (which is deficient in sebaceous glands and sometimes also in sweat glands).

Xeroderma pigmentosum is a rare disease, usually appearing in childhood, in which the skin atrophies (wastes away) and wrinkles. There is a familial tendency. Sufferers have photophobia (abnormal sensitivity of the eyes to light), and the warty and “keratolytic” lesions of the disease quickly become malignant if exposed to sunlight. Sufferers must be protected from the sun. The skin has the appearance of very old skin even in young people.

Xe`ro*der"ma (?), n. [NL., fr. Gr. dry + skin.] Med. (a)



A skin disease characterized by the presence of numerous small pigmented spots resembling freckles, with which are subsequently mingled spots of atrophied skin.


© Webster 1913.

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