• Richard O'Brien
• Fort O'Brien
• Late Night with Conan O'Brien
• Flann O'Brien
• Henry O'Brien
• Conan O'Brien
• Conan O'Brien's Commencement Speech for the Harvard Class of 2000
• George O'Brien Wyndham, 3rd Earl of Egremont
• Ed O'Brien
• Mary O'Brien
• Pat O'Brien's
• O'Brien (user)
• Cassandra O'Brien
• Miles O'Brien
• George O'Brien
• Kate O'Brien
• Keiko O'Brien
• Tina O'Brien
• niall (user)
• Cathy O'Brien
• Molly O'Brien
• John O'Brien
• Niall Quinn
• Edna O'Brien
• James O'Brien
• Niall of the Nine Hostages
• Stephen O'Brien
• Willis H. O'Brien
• Niall Ferguson
• Robert C. O'Brien
• Charles O'Brien, the Irish Giant

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