A general term to describe the central street or avenue of a town or city in the United States of America(USA). Most of the time, this is called Main Street, but sometimes it is some other popular street name like Park, or State..

On this street, you can find many businesses central to the community, as well as fast food joints, parks, and other farmiliar things. Due to the centrality of this street, it is often "Ave" in Cruising the Ave. If there is a parade in your town, it will probably pass through Main St, USA.