When *HE* comes back, he is going to be very, very hardcore anime. I picture him as wearing somewhat ornate, but worn leathers, riding a souped-up futuristic grav-cycle, blasting seven kinds of unholy out of all and sundry with divine telekenetic powers. He'll have those freaky big eyes, and hair that blows in the wind *just* right, as he stands proud in a mocking profile shot upon some tall promentary of rubble; and that's just before things get really weird.
Immediately after the tribulation of those days shall the sun be darkened, and the moon shall not give her light, and the stars shall fall from heaven, and the powers of the heavens shall be shaken: 30 And then shall appear the sign of the Son of man in heaven: and then shall all the tribes of the earth mourn, and they shall see the Son of man coming in the clouds of heaven with power and great glory (Matthew 24).
...If you can't see the this as just Akira on a grander scale, then you really aren't trying...
John the Revelator in Revelation 6:
12 And I beheld when he had opened the sixth seal, and, lo, there was a great earthquake; and the sun became black as sackcloth of hair, and the moon became as blood;
13 And the stars of heaven fell unto the earth, even as a fig tree casteth her untimely figs, when she is shaken of a mighty wind.
14 And the heaven departed as a scroll when it is rolled together; and every mountain and island were moved out of their places.
15 And the kings of the earth, and the great men, and the rich men, and the chief captains, and the mighty men, and every bondman, and every free man, hid themselves in the dens and in the rocks of the mountains;
16 And said to the mountains and rocks, Fall on us, and hide us from the face of him that sitteth on the throne, and from the wrath of the Lamb:
17 For the great day of his wrath is come; and who shall be able to stand?
What is this telling you? Jesus was E-boy last time he came down...all the peace, love, forgiveness and huggy warm stuff. For bringing us love, he was tacked up on a stick. I don't think he will have failed to learn from that little lesson. Next time it's the smackdown! Glowing eyes, big chunks of rock lifting up out of the earth's crust, actinic beams of slashy death cutting wailing petitioners into suprised halves, all sorts of weird organic morphing and evolving, and the big crunchy teeth. We won't stand a chance.