One of the @home projects which allows you to harvest otherwise unused CPU cycles, the most famous being SETI@home. Genome@home is a project at Stanford University to advance the amount knowledge in the field of genetics. In a nutshell this is what the project's program does:

DNA gets translated into protein. Genome@home take naturally existing protein sequences, makes alterations to them (that should be the same shape as the original protein, which is the most important thing about a protein), and then reverse translates these new proteins back into gene sequences; thus the project generates artificial genomes that, while not existing in the real world, should produce the same results as the existing genome (since they should produce proteins with the same shape).

The project hopes that by comparing these artificial genomes to natural ones, they will be able to gain a better understanding of genome evolution and how genes and proteins work. Their homepage lists some of the applications of the project as:

  • engineering new proteins for medical therapy
  • designing new pharmaceuticals
  • assigning functions to the dozens of new genes being sequenced every day
  • understanding protein evolution

The project gets it's protein information from the Protein Database (PDB), which can be found at http://ww.pdb.org. The protien shapes were all found with X-ray crystallography. Genome@home has a sister project, Folding@home whose goal is to find the shape of proteins via computer simulation.


The Genome@home project can be found at http://genomeathome.stanford.edu/.

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