DNase footprinting is a lab technique
used to find out which segments of a DNA molecule
are protected by DNA
s from attack
by endonuclease enzyme
s. The enzyme
s will break down DNA into smaller fragments by cleaving its phosphodiester
bonds. The technique uses gel electrophoresis
to find out which parts of the DNA
have sites for protein
s to attach to by comparing DNA
which has been in the presence of DNA
s with DNA that is "pure."
From the BioTech Dictionary at http://biotech.icmb.utexas.edu/. For further information see the BioTech homenode.