Maternal blood sampling for fetal blood cells

created by Prakash

(thing) by Prakash (7.4 y) (print) ? (I like it!) Thu Dec 21 2000 at 7:22:34

Maternal blood sampling for fetal blood cells
This is a new technique that makes use of the phenomenon of fetal blood cells gaining access to maternal circulation through the placental villi. Ordinarily, only a very small number of fetal cells enter the maternal circulation in this fashion (not enough to produce a positive Kleihauer-Betke test for fetal-maternal hemorrhage). The fetal cells can be sorted out and analyzed by a variety of techniques to look for particular DNA sequences, but without the risks that these latter two invasive procedures inherently have. Fluorescence in-situ hybridization (FISH) is one technique that can be applied to identify particular chromosomes of the fetal cells recovered from maternal blood and diagnose aneuploid conditions such as the trisomies and monosomy X. The problem with this technique is that it is difficult to get many fetal blood cells. There may not be enough to reliably determine anomalies of the fetal karyotype or assay for other abnormalities.

Please check out

Prenatal Diagnosis Overview

Ultrasound in PN Diagnosis

Amniocentesis

Chorionic Villus Sampling

printable version
chaos

Synthetic blood substitute	Chorionic Villus Sampling	Ultrasound in Prenatal Diagnosis	Amniocentesis
Placenta	Half A Person	Please tell me everything, this means you, I am hungry and also	karyotype
Prenatal Diagnosis - Overview

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